Watch the trailer for House of Gucci
Leto sports a receding hairline, moustache, heavy facial prosthetics and a rip Italian accent in the first look teaser.
Gaga portrays Patrizia Reggiani, the ex-wife of Maurizio Gucci, played by Adam Driver.
Maurizio was the grandson of Gucci’s founder and was murdered in 1995 by a hitman hired by his former spouse.
Driver, meanwhile, is seen in a pinstriped suit and aviator-style glasses, and Al Pacino and Jeremy Irons are also introduced as members of the cast.
House Of Gucci is Gaga’s first film since her Oscar-nominated turn in 2018’s A Star Is Born.
Lady Gaga fans were suitably thrilled by the first trailer with many tweeting their enthusiasm for the film.
In a case that captivated Italy, Gucci, at one time the head of the revered fashion house, was shot and killed by a hitman outside his office in 1995.
Reggiani, a socialite and high fashion personality, was convicted of orchestrating the murder.
In an attempt to get the verdict overturned, her two daughters argued a brain tumour had affected her behaviour.
She was jailed in 1998 and eventually freed in 2016.
Filming for House Of Gucci has taken place in various locations across Italy.
House of Gucci will be in UK cinemas 26 November 2021.